Actor Anne Heche suffered a devastating brain injury from a fiery car crash last week and is not expected to survive, a spokesperson for her family said in a statement Thursday night.

Unfortunately, due to her accident, Anne Heche suffered a severe anoxic brain injury and remains in a coma, in critical condition. She is not expected to survive, the statement, which was provided to several media outlets, said.

It has long been her choice to donate her organs and she is being kept on life support to determine if any are viable, the statement added.

A severe anoxic injury occurs when the brain is deprived of oxygen for a sustained amount of time and suffers cell death.

Heche, 53, remained in a coma late Thursday at the Grossman Burn Center at West Hills Hospital. She suffered burns that required surgery as well as lung injuries, The Associated Press reported.

Heche crashed into a house in the Mar Vista community of Los Angeles last Friday. According to the Los Angeles Fire Department, the car became engulfed in flames; much of the home was also destroyed by the fire.

Heche had drugs in her system at the time of the crash and is being investigated for possibly driving under the influence, police said Thursday.