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Posted: 2014-08-28T14:09:18Z | Updated: 2017-12-07T03:20:09Z

We all know that antiperspirants work differently than deodorants, but there's another big distinction between the two that you may not be aware of -- and it could make all the difference.

Dr. Dee Anna Glaser, president and founding member of the International Hyperhidrosis Society, says timing is everything when it comes to controlling sweat . Unlike deodorant, the best time to apply your antiperspirant is before bed.

While we sleep, we have "just the right amount of baseline sweating coming to the skin," Glaser explains in the above video from #OWNSHOW . "That helps to grab onto the active ingredient, bring it down into the sweat duct, and make a little plug."

If we apply antiperspirant in the morning, our basal level of sweat production is a bit too high, she says. "So no matter if you're using a regular antiperspirant or you're actually using a prescription, or you're using a clinical strength, you're going to get the best results if you put it on at night."

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Don't bother to re-apply the next morning: "Even if you shower or shave in the morning, you're not going to wear out the efficacy," she says.