April 24 (Reuters) - The U.S. Food and Drug Administration on Friday cautioned against the use of malaria drugs, hydroxychloroquine and chloroquine, in COVID-19 patients outside of hospitals and clinical trials, citing risks of serious heart rhythm problems.

The agencys announcement comes a day after the European Unions drug regulator warned of the drugs side effects and urged medical professionals to closely monitor patients on the medicines.

The FDA said it was aware of increased use of these medicines through outpatient prescriptions and the drugs could cause abnormal heart rhythms and dangerously rapid heart rate .

Decades-old hydroxychloroquine has been touted by U.S. President Donald Trump as a game changer in the fight against the novel coronavirus and anecdotal reports that it may provide some benefit have spurred sales of the drug.

However, the drug provided no benefit and potentially higher risk of death for patients at U.S. veterans hospitals, according to an analysis that was submitted for expert review earlier this week.

The FDA has allowed healthcare providers to use the drug for COVID-19 through its emergency use authorization, but the drug is not approved to treat the disease.

The heart rhythm risks may increase when the medicines are combined with other drugs, such as antibiotic azithromycin, as well as in patients with existing heart and kidney disease, the agency said on Friday .

(Reporting by Saumya Sibi Joseph and Manas Mishra in Bengaluru; Editing by Aditya Soni)