Sen. John Barrasso (R-Wyo.) announced Thursday that his wife, Bobbi Barrasso, had died following a two-year battle with glioblastoma brain cancer.

After a courageous battle with cancer, Bobbi is now at peace and at home with the Lord, he said in a statement , noting that she died in Casper, Wyoming.

The senator is the chair of the Senate Republican Conference and the third-ranking member of his partys leadership in the chamber. He spent 24 years as an orthopedic surgeon before entering politics in 2003, and has served in the Senate since 2007. He has three children with his late wife.

In addition to being a devoted wife and mother, Bobbi was a leader, fierce advocate for Wyoming, and friend to everyone she met, he said in Thursdays statement. We miss her dearly. On behalf of our entire family, we thank everyone for your prayers and continued support as we remember her and grieve together.