If I dont interrupt Blythe Danner and John Lithgow soon, they might never shut up.

Danner and Lithgow are sitting in a conference room at HuffPosts New York office, signing posters for their new movie and chatting back and forth as I ask which friends they have in common. Later, their rapid-fire crosstalk will be impossible to transcribe. Mentions of Meryl Streep, Rosemary Harris, Christopher Walken, Mandy Patinkin, Sam Waterston and Mary Beth Hurt ensue.

I always thought, With a name like that, shes not going to go anywhere, Lithgow says of Streep. He recalls his and Danners patter on the films set: This is the way we talked the entire time. We wore everybody out. All the makeup people, they thought we were two cranky old fools.

After the veteran actors are done scribbling a few dozen signatures apiece, they settle in and offer professional-grade attention. Danner seems unsure where she is at the moment And you are with ...? she asks, and I remind her this is a HuffPost interview but I guess thats the way it goes when youre being herded around the city by publicists for a day full of press.

The Tomorrow Man , which opened in select theaters Wednesday, is a romantic dramedy starring Lithgow as a divorced doomsday prepper who spends most of his time stocking a fallout shelter and posting comments online about apocalyptic conspiracy theories. In a supermarket parking lot, he meets a widow with her own set of neuroses, played by Danner. From there, they embark on a slow and steady courtship.

Danner, 76, and Lithgow, 73, dont recall the first time they met. It was probably sometime in the early 1970s, when they were both rising stars in the New York theater sphere. Across countless plays, films and TV series, Danners and Lithgows careers have only accelerated. In the 90s, they indoctrinated their children in the business. Yes, that means Gwyneth Paltrow, but also her brother, Jake, who has directed episodes of NYPD Blue and Boardwalk Empire. Lithgows son Ian starred alongside his father in the popular sitcom 3rd Rock from the Sun.

As our half-hour conversation progresses, Danner and Lithgow talk about their careers and the state of the industry, including controversial former collaborators like Bob Fosse and Woody Allen, as well as Streep, Goop, Broadway and that time Danners au pair almost burned down her house. But first, because its only fitting, we discuss the end times.