Cartoonist Al Jaffee has died the age of 102 in New York City.

The artists granddaughter Fani Thomson confirmed the news to The New York Times on Monday, citing the cause as multi-system organ failure.

Jaffee, born in 1921, started his career as a comic book artist before beginning his run at Mad in 1955.

One of the humor magazines most prolific illustrators, Jaffee was credited with the invention of its iconic Fold-In feature. The zany back covers, initially a subversive twist on Playboys centerfolds, became one of the magazines hallmarks after being introduced in 1964.