General Hospital actor Tyler Christopher, who appeared in over a thousand episodes of the hit daytime soap, has died at age 50, his colleagues from the show confirmed Tuesday.

Christopher died of a cardiac event in his San Diego apartment, his former General Hospital co-star Maurice Benard announced on Instagram.

Tyler was an advocate for better mental health and substance use treatment who openly spoke about his struggles with bipolar depression and alcohol, Benard wrote in a tribute . We are beyond devastated by the loss of our dear friend and pray for his children and his father.